Dihydrotestosterone (DHT)
Description:
5-αDHT measurement is used in:
- Identifying patients with 5 alpha-reductase deficiency.
- Androgenic alopecia (male-pattern baldness).
- Monitoring patients receiving 5 alpha-reductase inhibitor.
- In idiopathic hirsuitism about 40% of the patients have an increased DHT level.
- Identifying patients with 5 alpha-reductase deficiency.
- Androgenic alopecia (male-pattern baldness).
- Monitoring patients receiving 5 alpha-reductase inhibitor.
- In idiopathic hirsuitism about 40% of the patients have an increased DHT level.
Clinical details:
DHT is a C19 steroid and is generated by reduction of testosterone by 5-alpha reductase.
Serum concentrations of testosterone and DHT are very variable within the first 6 months of life and through puberty and baseline values may be at the limit of sensitivity. In pre-pubertal patients, values should be assessed before and after treatment with hCG.
Serum concentrations of testosterone and DHT are very variable within the first 6 months of life and through puberty and baseline values may be at the limit of sensitivity. In pre-pubertal patients, values should be assessed before and after treatment with hCG.
Reference range:
PDF (460Kb)
Units:
nmol/L
Department:
Location:
Sample type and Volume required:
Clotted (yellow SST) preferred, but EDTA plasma also accepted. Volume required: 250uL; Absolute minimum required: 150uL.
Turnaround time:
10 working days or 14 days
Storage and transport:
Serum aliquots are stable at 4°C for 24 hours. Store at -20°C thereafter.
Contacts:
Steroid Laboratory at King's College Hospital
020 3299 4131
King's College Hospital
Denmark Hill
London SE5 9RS
Denmark Hill
London SE5 9RS
Laboratory:
Last updated: 03/10/2022
