Zinc protoporphyrin (ZPP)
Description:
ZPP is a test offered by the SAAS Porphyria Service in Reference Biochemistry at King’s College Hospital. Quantitative measurement of ZPP is reported with free erythrocyte protoporphyrin (FEP) using fluorescence spectroscopy
Clinical details:
ZPP is present in red blood cells when there is not enough iron available to form haem and zinc combines with protoporphyrin in the absence of iron. ZPP is elevated in patients with X-linked protoporphyria (XLPP), iron deficiency anaemia and chronic exposure to lead
Reference range:
<800 nmol/L red cells
Synonyms or keywords:
ZPP
Department:
Location:
Sample type and Volume required:
5 – 10 ml whole blood collected into EDTA or heparin. Separate red cells and plasma if delay in dispatch. Specimens should be protected from light.
Turnaround time:
1-2 weeks
Storage and transport:
Specimens can be sent by first class post without ice packs. Specimens are stable for several weeks if frozen while awaiting despatch.
Contacts:
Reference Biochemistry Department at King's College Hospital
020 3299 4107
King's College Hospital
Denmark Hill
London SE5 9RS
Denmark Hill
London SE5 9RS
Porphyrins and Gastrointestinal Laboratory at King's College Hospital
Porphyrins - 020 3299 3856
King's College Hospital
Denmark Hill
London SE5 9RS
Denmark Hill
London SE5 9RS
Last updated: 03/02/2017
