Treponema pallidum Serology
Description:
Serology tests for diagnosis, confirmation and monitoring of Treponema pallidum infection.
A CMIA (chemiluminescent microparticle immunoassay) is the screening test. Confirmatory tests are made with an additional qualitiative EIA and/or a specific particle agglutination test (TPPA). All new and past CMIA positives are tested for Rapid Plasma Reagin (RPR).
A CMIA (chemiluminescent microparticle immunoassay) is the screening test. Confirmatory tests are made with an additional qualitiative EIA and/or a specific particle agglutination test (TPPA). All new and past CMIA positives are tested for Rapid Plasma Reagin (RPR).
Clinical details:
All suspected cases should be discussed with a sexual health specialist.
Synonyms or keywords:
Chancre, RPR, VDRL, TPPA, TPHA, Spirochete, Treponemal
Department:
Location:
Sample type and Volume required:
2.5 – 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum) or Cerebrospinal Fluid (CSF) in a sterile universal container with no additives.
Turnaround time:
3 working days
Storage and transport:
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Contacts:
Infection Sciences Department at St Thomas' Hospital
020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730
Laboratory:
Last updated: 25/11/2017
