HLA Typing (Class I and Class II) for Solid Organ and Stem Cell Transplantation

Description: 
A variety of methods and technologies are used, including Next Generation Sequencing (NGS), PCR-SSP and PCR-SSOP (Luminex) to determine HLA Class I (HLA-A, B, C) and HLA Class II (DRB1/3/4/5, DQB, DQA, DPB, DPA) alleles. The results achieved can be reported at a variety of resolution from low (1st field) to high (3rd Field) as required. Routinely all initial HLA types will be tested by NGS to high resolution, 2nd Field, unless otherwise requested.
Clinical details: 
HLA typing for work up for solid organ transplant or stem cell transplantation - recipient or donor – to allow for assessment of HLA compatibility.
Related condition or disease: 
Solid organ transplantation, Stem cell transplantation
Reference range: 

none

Synonyms or keywords: 
HLA typing, transplant
Units: 
none
Department: 
Clinical Transplantation Department
Location: 
Guy's Hospital
Sample type and Volume required: 
10ml EDTA blood
Call in advance: 
No
Turnaround time: 
10 working days
Special sample instructions: 

none

Criteria for acceptance / rejections of sample
Storage and transport: 
UN3373 packaging, room temperature
Time limit for extra tests: 
none
Contacts:
Clinical Transplantation Department at Guy's Hospital
Laboratory Enquiry: 020 7188 1540
Clinical Transplantation Department
Guy's Hospital
Borough Wing - 3rd Floor
Great Maze Pond
London SE1 9RT
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Clinical Transplantation Laboratory at Guy's Hospital

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Last updated: 11/08/2023