Glycosaminoglycans & oligosaccharides (GAGs/mucopolysaccharides & oligos)

Description: 
Quantitative & 2D electrophoresis for GAGs, TLC for oligosaccharides
Related condition or disease: 
Mucopolysaccharidosis, Hurler, Scheie, Hunter, Sanfilippo, Morquio, Maroteaux-Lamy, Sly, GM1-gangliosidosis, fucosidosis, α-mannosidosis, sialidosis, aspartylglycosaminuria or N-acetylneuraminic acid storage disease (Salla disease)
Reference range: 

Age specific ranges for GAGs, oligosaccharide testing is qualitative

Synonyms or keywords: 
Urine screening tests, Glycosaminoglycans, GAGs, Mucopolysaccharides, Mucopolysaccharidosis, oligosaccharides
Department: 
Genetics Department
Location: 
Guy's Hospital
Sample type and Volume required: 
Fresh urine (plain universal, no preservatives) minimum volume 5ml. Urines with pH greater than 8 and/or creatinine less than 1mmol/L are likely to be unsuitable for assay and may be rejected.
Call in advance: 
No
Turnaround time: 
5 weeks
Criteria for acceptance / rejections of sample
Storage and transport: 
Send by first-class post, store frozen if not sent immediately
Contacts:
Biochemical Genetics Laboratory at Guy's Hospital
Genetics Department
Tower Wing - 5th Floor
Guy's Hospital
Great Maze Pond
London SE1 9RT

T: 020 7188 2591/2592
F: 020 71887275
E: ViapathBiochemicalGenetics@gstt.nhs.uk
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Biochemical Genetics Laboratory at Guy's

Print as a PDF

Last updated: 17/12/2019