Glucose 6 Phosphate Dehydrogenase Assay

Description: 
G6PD deficiency is a common hereditary enzyme deficiency causing varying degrees of haemolytic anemia; can cause favism, some drug induced haemolytic anemias, and chronic nonspherocytic haemolytic anemia. Any samples with a deficient screen or reticulocyte levels >150 x 10 9/L will have a G6PD assay performed.
Reference range: 

5.2 - 11.5 IU/g Hb

Department: 
Special Haematology Department
Location: 
King's College Hospital
Sample type and Volume required: 
Minimum 1 ml EDTA blood. If more than one enzyme assay is required then > 1.0 ml of blood will be required. Full blood count and reticulocyte must be performed and results sent with samples.
Turnaround time: 
10 working days
Special sample instructions: 

Blood transfusion within the last four months will affect results. Any red cell transfusion given must be declared on the request form.

Raised reticulocyte levels and/or raised Wbc levels may affect assay.

Criteria for acceptance / rejections of sample
Storage and transport: 
Samples can be sent first class post. Samples must be received in the laboratory within 3 days of collection. If there is a delay in sending store at 4°C and send a normal sample collected on the same day to act as a travel control.
Cost: 
Please contact Business Development for pricing enquiries
Time limit for extra tests: 
Depends on tests required. Contact laboratory for further details.
Contacts:
Red Cell Centre - Protein Laboratory
020 3299 2455
kch-tr.redcelllab@nhs.net
c/o Central Specimen Reception
Blood Sciences Laboratory
Ground Floor Bessemer Wing
King’s College Hospital
Denmark Hill
London SE5 9RS
Mon-Fri, 9.00am-5.30pm
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Red Cell Centre - Protein Laboratory

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Last updated: 08/01/2020