Cytogenetic Investigations for Infertility - Y Chromosome Microdeletions
Description:
Y chromosome microdeletions can be investigated using quantitative fluorescence PCR (QF-PCR).
Clinical details:
Scientific studies have demonstrated that Y-chromosome microdeletions are responsible for up to 10% of male infertility.
Synonyms or keywords:
Karyotyping, G-banded chromosome analysis, Chromosomes.
Department:
Location:
Sample type and Volume required:
5ml of peripheral blood in a lithium heparin bottle
Turnaround time:
42 days
Special sample instructions:
Request form available at: https://southeastgenomics.nhs.uk/wp-content/uploads/2023/08/SE-GLH-Non-WGS-Genetic-Test-Request-Form-August-2023-v1.5.pdf
- R411 Y Chromosome microdeletions
Include the relevant R code (above) on the referral form; for further details and the eligibility criteria for testing please see https://www.england.nhs.uk/publication/national-genomic-test-directories/
Storage and transport:
Samples should arrive within 72 hours (preferably 24 hours) of sampling.
Cost:
On application
Time limit for extra tests:
Do not spin down or freeze samples before sending.
Contacts:
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory:
Last updated: 26/10/2023
