Haemoglobin Mass Spectrometry

Description: 
The haemoglobin mass spectrometry assay is used for the confirmation of Hb S, C, E, DPunjab, OArab, Lepore, G Philladelphia and Stanleyville. The panel includes the common and clinically significant haemoglobins.
Clinical details: 
Confirmation of Hb S, C, E, DPunjab, OArab, Lepore, G Philladelphia and Stanleyville.
Related condition or disease: 
Sickling disorders and carriers of common alpha gene variants.
Reference range: 

n/a

Synonyms or keywords: 
HBMS, MSMS, haemoglobin tandem mass spectrometry, mass spec, variant identification
Department: 
Special Haematology Department
Location: 
St Thomas' Hospital
Sample type and Volume required: 
Whole blood collected into EDTA. The minimum acceptable volume is 500μL.
Turnaround time: 
1 working week
Criteria for acceptance / rejections of sample
Storage and transport: 
Samples should be stored refrigerated if not being transported immediately. Please send samples within 7 days of venepuncture. Samples may be transported at ambient temperature.
Contacts:
Special Haematology Department at Guy's and St Thomas' Hospital
St Thomas’ Hospital
5th Floor - North Wing
Westminster Bridge Road
London SE1 7EH
Telephone - 0207 188 8189

Guy’s Hospital
4th Floor - Southwark Wing
Great Maze Pond
London SE1 9RT
Telephone - 020 7188 3421

Red Cell Laboratory at Guy's and St Thomas' Clinical Advisory Service
Monday - Friday 09:00 - 17:00 (adult):
rachel.kesse-adu@gstt.nhs.uk and Kate.Gardner1@gstt.nhs.uk
Monday - Friday 09:00 - 17:00 (paediatric): Samah.Babiker@gstt.nhs.uk
Red Cell Laboratory at Guy's and St Thomas' Technical Advisory Service
Monday - Friday 09:00 - 17:00
yvonne.daniel@gstt.nhs.uk
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Red Cell Laboratory at Guy's and St Thomas' Hospital
Red Cell Referral Form
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Last updated: 29/09/2022