Haemoglobin Variant Identification

The Red Cell Protein Laboratory can provide a variant identification service based on a comprehensive range of identification methods. Initial analysis is by HPLC which will screen for any haemoglobin variants. Further tests will be performed depending on HPLC results. This could include solubility test, acid electrophoresis or HbH bodies. For uncommon haemoglobin variants further analysis by iso-electric focussing can be undertaken. All samples sent for analysis will get an interpretive comment relevant to the clinical details. Molecular analysis can be undertaken by the Prenatal diagnosis section.