Living donor crossmatch

Description: 
Flow cytometry analysing IgG binding to donor T and B lymphocytes from peripheral blood
Clinical details: 
In solid organ transplantation the presence of HLA donor specific antibodies is associated with graft loss and graft dysfunction. Flow cytometric (FCXM) crossmatch tests are used to identify HLA donor specific antibodies. A crossmatch test is performed in living kidney transplantation
Related condition or disease: 
Kidney transplantation
Stem cell transplantation
Reference range: 

> 2.3 - positive

Synonyms or keywords: 
crossmatch
Units: 
RMF
Department: 
Clinical Transplantation Department
Location: 
Guy's Hospital
Sample type and Volume required: 
donor - 20mls EDTA blood
recipient - 5ml clotted blood
Call in advance: 
Call 020 7188 1540 to book in a crossmatch
Turnaround time: 
2 days
Special sample instructions: 

samples should be bled on day of testing

Criteria for acceptance / rejections of sample
Storage and transport: 
UN3373 packaging
Time limit for extra tests: 
none
Contacts:
Clinical Transplantation Department at Guy's Hospital
Laboratory Enquiry: 020 7188 1540
Clinical Transplantation Department
Guy's Hospital
Borough Wing - 3rd Floor
Great Maze Pond
London SE1 9RT
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Clinical Transplantation Laboratory at Guy's Hospital

Print as a PDF

Last updated: 07/08/2015