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1st August 2013

Urinary excretion of porphyrins, porphobilinogen and δ-aminolaevulinic acid following an attack of acute intermittent porphyria.

Joanne T Marsden, David C Rees

1st August 2013

How I treat heterozygous hereditary antithrombin deficiency in pregnancy

Untreated hereditary antithrombin deficiency in pregnancy is associated with maternal venous thromboembolism (VTE) and possibly with fetal loss.

Bramham K, Retter A, Robinson SE, Mitchell M, Moore GW, Professor Beverley Hunt

31st July 2013

21-Hydroxylase deficiency in the neonate – trends in steroid anabolism and catabolism during the first weeks of life

Sofia Christakoudi, David A. Cowan, Georgios Christakudis

28th July 2013

Epicardial fat and vascular risk: a narrative review

We comment on the associations between epicardial adiposity and cardiovascular disease (CVD) and associated risk factors.

Katsiki N, Mikhailidis DP, Professor Anthony S. Wierzbicki

28th July 2013

New therapies to reduce low-density lipoprotein cholesterol

Lipid-lowering is an intervention that reduces atherosclerosis and its complications.

Professor Anthony S. Wierzbicki, Viljoen A , Hardman TC, Mikhailidis DP

27th June 2013

Measurement of infliximab and anti-infliximab antibodies - analytical aspects and clinical implications

Commercial assays for monitoring Infliximab (IFX) and anti-drug antibodies (ADAb) are currently available.

Nick Unsworth, Zehra Arkir, P. Irving, M.G.Ward, G. Richards

27th June 2013

Lipid-lowering agents

The role of lipid lowering in reducing the risk of mortality and morbidity from cardiovascular disease (CVD) is well established.

Ewang-Emukowhate M, Professor Anthony S. Wierzbicki

14th June 2013

The Mechanism of Allopurinol Induced TPMT Inhibition

Up to 1/5 of patients with wildtype thiopurine-S-methyltransferase (TPMT) activity prescribed azathioprine (AZA) or mercaptopurine (MP) demonstrate a skewed drug metabolism in which MP is preferentially methylated to yield methylmercaptopurine (MeMP)

Blaker PA, Arenas-Hernandez M, Smith MA, Shobowale-Bakre EA, Fairbanks L, Irving PM, Sanderson JD, Marinaki AM

12th June 2013

Pain, purpura and curly hairs

This review follows a patient presenting with symptoms of Vitamin C deficiency (scurvy) at St. Thomas' Accident and Emergency Department, outlining symptoms, diagnosis and successful treatment.

J D Fleming, B Martin, David Card and J E Mellerio

12th June 2013

Diabetes and gout: efficacy and safety of febuxostat and allopurinol.

Assess influences of demographics and co-morbidities of gout patients with or without diabetes on safety and efficacy of urate-lowering agents.

M. A. Becker, P. A. MacDonald, Professor Beverley Hunt, R. L. Jackson

Last updated: 18/05/2015

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